ceesdekker No Further a Mystery

‘Yes, that is certainly about right. I seek out a Actual physical knowledge of Organic units within a base-up way. I do think you can distinguish 3 strains of investigate in my group at this time. The very first worries chromosome composition: how do you get yourself a metre-very long DNA polymer folded and organised in this kind of microscopic cell? We've got formulated visualisation strategies that let us to check how, for example, SMC proteins loop DNA (video clip on Youtube) in order to Construct up chromosomes.

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Being a individual, I possess the biblical assignment to check out and use everything in creation for the advantage of my neighbour. I never encounter any conflict involving religion and science. On the contrary, my faith stimulates me to perform science, to be open-minded in the world.’

I am able to barely think about how I, like a geneticist, would have the capacity to understand basic physics, let alone compete at the top. How did you go over it?

We produce level-of-care diagnostics exam of neglected tropical conditions inside of resource-confined options, depending on Crspr/Cas9 detecting of pathogen’s DNA in physique fluids.

Case in point (3) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim of the pore is highlighted in purple, as well as a 3D rendering of the movement from the DNA rod is exhibited.

We form microorganisms into types that deviate from their all-natural phenotype. Particularly, I'll exhibit our capacity to form live E. coli bacteria into novel styles for example rectangles, squares, triangles and circles.

He also discovered time to put in writing a number of textbooks, send Practically forty thousand tweets and lead An effective investigate group at Delft College of Technologies. ‘It doesn’t sense like work’, he states. ‘I’m just terribly curious.’

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Resolving the action dimensions in condensin-driven DNA loop extrusion identifies ATP binding since the phase-creating method

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2001, discovery of one-electron transistors at home temperature dependant on nanotubes; realization of first logic circuits with carbon nanotube devices; and discovery from the molecular structure of DNA restore enzymes with AFM

Developments in nanotechnology in the nineteen nineties made developing electronic devices from single molecules a possibility. Cees Dekker recounts how his team produced a space-temperature transistor depending on just one carbon nanotube.

Supercoiling-dependent DNA binding: quantitative modeling and apps to bulk and single-molecule experiments